Aniba canelilla is an evergreen tree native to the Amazon rainforest. It has reddish bark and yellow flowers. Canelilla bark and leaves have a cinnamon odor due to1-nitro-2-phenylethane.
Cardiovascular effects of intravenous (i.v.) treatment with the essential oil of the bark of Aniba canelilla were investigated in normotensive rats. In both pentobarbital-anesthetized and conscious rats, i.v. bolus injections of Aniba canelilla (1 to 20 mg/kg) elicited similar and dose-dependent hypotension and bradycardia.
Our data show that i.v. treatment of rats with Aniba canelilla induces dose-dependent hypotension and bradycardia, which occurred independently.
The bradycardia appears mainly dependent upon the presence of an operational and functional parasympathetic drive to the heart. However, the hypotension is due to an active vascular relaxation rather than withdrawal of sympathetic tone.
This relaxation seems partly mediated by an endothelial L-arginine / nitric oxide pathway through peripheral muscarinic receptor activation (endothelium-dependent relaxation) and predominantly through an inhibition of calcium inward current (endothelium-independent relaxation).
The essential oil is extracted by steam distillation from wood chippings and produces a colourless to pale yellow liquid. It has a floral spicy scent. Traditionally, rosewood oil is used for acne, colds, coughs, dermatitis, fevers, frigidity, headaches, infections, nausea, nervous tension, skin care and wounds.
Antinociceptive effect - Antinociceptive activity of 1-nitro-2-phenylethane, the main component of Aniba canelilla essential oil.
Mama Juana is a combination of several herbs sold as a sex potion. Mama Juana comes from the Dominican Republic. Aniba Canelilla is one of the herbs often found in Mama Juana.